FITC Anti-Human CD274/PD-L1 Antibody[29E.2A3]
PHA-stimulated (3 days) human peripheral blood lymphocytes are stained with FITC Anti-Human CD274/PD-L1 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control PE (empty black histogram).
货号:GFH1133C
价格: ¥1740.00 ¥660.00 ¥2640.00
产品详情
CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
Alternate NamesB7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG2b, κ
ConjugateFITC
Concentration5 μL/Test
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋
产品结果图
PHA-stimulated (3 days) human peripheral blood lymphocytes are stained with FITC Anti-Human CD274/PD-L1 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control PE (empty black histogram).
PHA-stimulated (3 days) human peripheral blood lymphocytes are stained with FITC Anti-Human CD274/PD-L1 Antibody (filled gray histogram) or Mouse IgG1 Isotype Control PE (empty black histogram).
相关文献
-
期刊:CHEMICO-BIOLOGICAL INTERACTIONS
影响因子:4.7
相关产品: High Sensitivity Mouse TNF-α ELISA Kit, Cu Colorimetric Assay Kit, Human TNF-α ELISA Kit, Human IFN-γ ELISA Kit, High Sensitivity Mouse IFN-γ ELISA Kit, FITC Anti-Human CD274 Antibody
-
期刊:Scientific Reports
DOI:10.1038/s41598-024-67437-4
影响因子:3.8
-
期刊:HUMAN IMMUNOLOGY
DOI:10.1016/j.humimm.2024.111168
影响因子:3.1
相关产品: FITC Anti-Human CD274 Antibody, MCF7 [MCF-7] Cells Line, MDA-MB-231 Cells Line