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BMP-7, Human, Recombinant-1

英文名称:BMP-7, Human, Recombinant

货号:GPCK372

价格: ¥36680.00 ¥7380.00 ¥1880.00 ¥51880.00

规格:
500μg 50μg 10μg 1mg
产品详情

产品信息

产品规格 500μg / 50μg / 10μg / 1mg
别名 bone morphogenetic protein 7;Osteogenic Protein-1 (OP-1);BMP7
表达宿主 E.coli
序列信息 MANVAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH with polyhistidine tag at the C-terminus.
检索号 P18075
分子量 14.00 kDa
表观分子量 12 kDa
标签 His Tag (C-term)
生物活性 Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is < 0.65 μg/mL.
纯度 >95% as determined by SDS-PAGE. Ni-NTA chromatography.
内毒素 < 0.1 EU/μg
制剂 The protein was lyophilized from a 0.2 μm filtered solution containing 1× PBS, pH8.0.
复融 It is recommended to reconstitute the lyophilized protein in sterile water to aconcentration not less than 100 μg/mL. Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.
储存条件 Lyophilized protein should be stored at -5~-20℃ for 1 year. Upon reconstitution, store at 2-8℃ for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10% FBS, 5% HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20℃ or -80℃ for 3-6 months.
运输条件 Ambient temperature or ice pack.
有效期 12个月
背景介绍 Bone Morphogenetic Protein-7 (BMP-7) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP7 can significantly inhibit TGF-β through binding with TGF-β receptor and trigger SMAD transcription factors, such as SMAD 1/5/8. It plays a vital role in inhibiting the expansion of kidney damage and promoting the differentiation of osteoblasts.
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