Beta-TC-6 -

文献(8) 说明书

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Beta-TC-6-1

英文名称：Beta-TC-6

货号：GCL-0322

规格：

1×10^6Cells/T25 1×10^6Cells/Vial×2Vials

产品详情

产品信息

物种	Mouse
生长特性	贴壁细胞
细胞形态	上皮细胞样
冻存条件	冻存液：55% 基础培养基+40% FBS+5% DMSO 温度：液氮
培养方案A（默认）	生长培养基：DMEM[GPM150210]+15% FBS[163210]+1% P/S[GPB180120] 培养条件：温度：37℃
推荐传代比例	1:2-1:4
推荐换液频率	2-3次/周

参考资料（来源文献）

背景描述	Beta-TC-6细胞来源于转基因小鼠中生长的一个胰肿瘤（胰岛素瘤），这种小鼠携带了大鼠胰岛素Ⅱ基因启动子调控的SV40早期基因的假基因结构。Beta-TC-6细胞包含大量的胰岛素和小量的胰高血糖素及生长抑素；Beta-TC-6细胞能响应葡萄糖而分泌胰岛素。
组织来源	胰；胰岛素瘤
细胞类型	肿瘤细胞
肿瘤类型	胰腺癌细胞
生物安全等级	BSL-2 [Cells contain SV40 viral DNA Sequences]
基因表达情况	insulin, glucagon, and somatostatin
保藏机构	ATCC; CRL-11506

相关文献

The odorant (R)-(-)-carvone promotes glucose-stimulated insulin secretion via the olfactory receptor Olfr1259 in pancreatic β-TC6 cells(2025)

期刊：ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

DOI：10.1016/j.abb.2025.110404

影响因子：3.8

相关产品： Beta-TC-6 Cells Line
Semaglutide alleviates the pancreatic β cell function via the METTL14 signaling and modulating gut microbiota in type 2 diabetes mellitus mice(2024)

期刊：LIFE SCIENCES

DOI：10.1016/j.lfs.2024.123328

影响因子：5.2

相关产品： Mouse INS ELISA Kit, DMEM (High glucose), with L-alanyl-L-glutamine, HEPES Medium, Beta-TC-6 Cells Line
Evaluating the In Situ Insulinotropic Effects of Pea Protein Hydrolysates Mediated by Active GLP-1 via a 2D and Dual-Layered Coculture Cell Model(2023)

期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

DOI：10.1021/acs.jafc.3c05583

影响因子：6.1

相关产品： Beta-TC-6 Cells Line, NCI-H716 [H716] Cells Line
Transepithelial Transport of the Bifunctional Peptide IPYWTY Indirectly Induced Insulin Release Mediated by Active GLP-1(2023)

期刊：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

DOI：10.1021/acs.jafc.3c04940

影响因子：6.1

相关产品： Beta-TC-6 Cells Line, NCI-H716 [H716] Cells Line
RGS7 silence protects palmitic acid-induced pancreatic β-cell injury by inactivating the chemokine signaling pathway(2023)

期刊：AUTOIMMUNITY

DOI：10.1080/08916934.2023.2194584

影响因子：3.500

相关产品： Beta-TC-6 Cells Line, NIT-1 Cells Line, HIT-T15 Cells Line
A peptide encoded by lncRNA MIR7-3 host gene (MIR7-3HG) alleviates dexamethasone-induced dysfunction in pancreatic β-cells through the PI3K/AKT signaling pathway(2023)

期刊：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DOI：10.1016/j.bbrc.2023.01.004

影响因子：3.100

相关产品： Beta-TC-6 Cells Line, 293T [HEK-293T] Cells Line
Silencing of DIRAS3 improves the proliferation and insulin secretion of palmitic acid-treated pancreatic β?cells through regulating PI3K/AKT signaling(2023)

期刊：International Journal of Diabetes in Developing Countries

DOI：10.1007/s13410-023-01240-1

影响因子：0.9

相关产品： Beta-TC-6 Cells Line, INS-1 Cells Line, RIN-m5F Cells Line, MIN6 Cells Line
Cdc42 upregulation under high glucose induces podocyte apoptosis and impairs β-cell insulin secretion(2022)

期刊：Frontiers in Endocrinology

DOI：10.3389/fendo.2022.905703

影响因子：6.055

相关产品： Beta-TC-6 Cells Line

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