APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
货号:GFH1132UE
价格: ¥2640.00 ¥780.00
产品详情
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Alternate NamesB7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
Clone No. HostRat
ReactivityMouse
IsotypeRat IgG2b, κ
ConjugateAPC
Concentration0.2 mg/mL
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋
产品结果图
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