APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2]
Staining of C57BL/6 murine splenocytes with FITC Anti-Mouse CD3 Antibody[17A2] and APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (left) or APC Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.
货号:GFH1132E
价格: ¥1080.00 ¥660.00 ¥1620.00
产品详情
CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
Alternate NamesB7H1PD-L1PDCD1L1PDCD1LG1PDL1;B7 homolog 1;B7-H;B7-H1;Programmed cell death ligand 1
Clone No. HostRat
ReactivityMouse
IsotypeRat IgG2b, κ
ConjugateAPC
Concentration5 μL/Test
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋
产品结果图
Staining of C57BL/6 murine splenocytes with FITC Anti-Mouse CD3 Antibody[17A2] and APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (left) or APC Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.
Staining of C57BL/6 murine splenocytes with FITC Anti-Mouse CD3 Antibody[17A2] and APC Anti-Mouse CD274/PD-L1 Antibody[10F.9G2] (left) or APC Rat IgG2b, κ Isotype Control (right). Total viable cells were used for analysis.
相关文献
-
期刊:Molecular Cancer
DOI:10.1186/s12943-025-02253-6
影响因子:27.7
-
期刊:INTERNATIONAL IMMUNOPHARMACOLOGY
DOI:10.1016/j.intimp.2025.114548
影响因子:4.8
-
期刊:SCANDINAVIAN JOURNAL OF IMMUNOLOGY
影响因子:4.1
相关产品: FITC Anti-Mouse MHC II Antibody, PE Anti-Mouse Ly6G Antibody, APC Anti-Mouse CD274 Antibody, PerCP Anti-Mouse/Human CD11b Antibody, PE/Cyanine7 Anti-Mouse CD11c Antibody, PE Anti-Mouse CD86 Antibody
-
VSV-CHIKV activates antitumor immunity by inducing pyroptosis in a melanoma model(2025)
期刊:Discover Oncology
DOI:10.1007/s12672-025-02788-6
影响因子:2.8
相关产品: APC Rat IgG2a, κ Isotype Control, APC Rat IgG2b, κ Isotype Control, APC Anti-Mouse CD279/PD-1 Antibody, APC Anti-Mouse CD274 Antibody, BHK-21 [C-13] Cells Line, B16 Cells Line, DMEM (High glucose) Medium
-
期刊:CARBOHYDRATE POLYMERS
DOI:10.1016/j.carbpol.2024.122659
影响因子:10.7
相关产品: FITC Anti-Mouse MHC II (I-A/I-E) Antibody, PE Anti-Mouse CD86 Antibody, APC Anti-Mouse CD274 Antibody
-
期刊:Anti-Cancer Agents in Medicinal Chemistry
DOI:10.2174/1871520623666230707112244
影响因子:2.8
相关产品: LLC [LL/2; LLC1] Cells Line, Phosphate Buffer (PBS, 1 ×), PerCP/Cyanine5.5 Anti-Mouse CD3 Antibody, APC Anti-Mouse CD274 Antibody, APC Anti-Mouse CD19 Antibody, APC Anti-Mouse CD8a Antibody, FITC Anti-Mouse CD4 Antibody