Anti-Human CD3-APC/CD4-FITC/CD8a-PE Cocktail

文献(2) 说明书

货号：GFHC0008

规格：

100 Tests 20 Tests 100 Tests × 2

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Background

This product is a FCM antibody cocktail made up of APC Anti-Human CD3 Antibody [Clone: OKT-3] (Mouse IgG2a, κ), FITC Anti-Human CD4 Antibody [Clone: RPA-T4] (Mouse IgG1, κ) and PE Anti-Human CD8a Antibody [Clone: OKT-8] (Mouse IgG2a, κ).; CD3 is a heterotetrameric protein consisting of a CD3γ, a CDδ and 2 CD3ε. It forms complex with TCR. OKT-3 recognize human CD3ε. Human CD3 is expressed on the surface of T cells and NKT cells.; CD4 is also called Leu-3 or T4. It's a single-chain type I transmembrane glycoprotein, mainly expressed on the surface of T cells, and monocytes/macrophages. In T cells, CD4 forms complex with TCR/CD3 and play important roles in T cell immunity. The target of HIV is CD4+ T cells. Reduction of CD4+ T cells is the main reason of defected immunity after HIV infection.; CD8 is mainly expressed on cytotoxic T cells and also some subpopulations of NK cells. CD8 forms dimer function. In most cells, CD8 is a heterodimer consisting of CD8a and CD8b, but in NK cells nearly all CD8 is homodimer of CD8a. CD8a can form co-receptor with MHC-I restricted TCR to promote T cell antigen recognition and activation.

Clone No.

OKT-3 , RPA-T4 , OKT-8

Reactivity

Human

Conjugate

APC;FITC;PE

Concentration

5 μL/Test

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

Storage

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiration Date

12个月

Shipping

冰袋

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联系我们

sales@procell.com.cn

400-999-2100

Anti-Human CD3-APC/CD4-FITC/CD8a-PE Cocktail

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