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AF/LE Purified Anti-Human HLA-G Antibody[87G]

说明书
  • AF/LE Purified Anti-Human HLA-G Antibody[87G]-1
  • AF/LE Purified Anti-Human HLA-G Antibody[87G]-2
AF/LE Purified Anti-Human HLA-G Antibody[87G]-1

JEG3 were stained with 0.2 μg AF/LE Purified Anti-Human HLA-G Antibody[87G] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.

货号:GF002910

价格: ¥420.00 ¥1248.00

规格:
100 μg 1 mg
产品详情
Background

HLA-G Antibody (4H84) is an IgG1 κ mouse monoclonal HLA-G antibody (also designated HLA major histocompatibility complex, class I, G antibody, human leukocyte antigen (HLA) G antibody, 45 kDa transmembrane class I human leukocyte antigen G antibody, chromosome 6p22 gene complex class 1G antibody, placenta trophoblast marker antibody, or fetal derived placental cell marker antibody) that detects the HLA-G protein of mouse, rat and human origin by WB, IP, IF and IHC(P). HLA-G Antibody (4H84) is available as both the non-conjugated anti-HLA-G antibody form, as well as multiple conjugated forms of anti-HLA-G antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an α or heavy chain, and a non-covalently associated protein, β-2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.

Alternate Names

HLA;MHC-G;HLA-G;HLA-G HLA-6.0 HLAG;HLA-G5;HLA-6.0;HLAG;alpha chain G;B2 microglobulin;class I;DADB-15K14.8;HLA 6.0;HLA class I histocompatibility antigen;HLA class I histocompatibility antigen alpha chain G;HLA class I molecule;HLA G;HLA G antigen;HLA G histocompatibility antigen class I G;HLA G3;HLA60;HLA-G histocompatibility antigen;Major histocompatibility complex class I G;MHC class I antigen;MHC class I antigen G;MHC G;TCA;T-cell A locus

Swissprot

P17693

Immunogen

Recombinant Human HLA-G protein

Clone No.

87G

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG2a, κ

Dilution

FCM 2 μg/mL(1×105-5×105 cells)

Conjugate

None (AF/LE)

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiration Date

12个月

Shipping

Ice bag

产品结果图

JEG3 were stained with 0.2 μg AF/LE Purified Anti-Human HLA-G Antibody[87G] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.

AF/LE Purified Anti-Human HLA-G Antibody[87G]-产品结果图-1

JEG3 were stained with 0.2 μg AF/LE Purified Anti-Human HLA-G Antibody[87G] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.

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