AF/LE Purified Anti-Human CD28 Antibody[CD28.2]

文献(2) 说明书

Human peripheral blood red blood cells were stained with 0.2 μg AF/LE Purified Anti-Human CD28 Antibody[CD28.2] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.

货号：GF11950

规格：

100 μg 1 mg

产品详情

Background

CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

Alternate Names

PAS;T-cell-specific surface glycoprotein CD;CD28;Tp44;CD28 antigen;CD28 molecule;GPSAT;GYPA;HGpMiX;MNS;PAS2;T-cell-specific surface glycoprotein CD28; T44

Swissprot

P10747

Immunogen

Recombinant Human CD28 protein

Clone No.

CD28.2

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG1, κ

Dilution

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Conjugate

None (AF/LE)

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM;Activ

Clonality

Monoclonal

Storage Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiration Date

12个月

Shipping

Ice bag