Recombinant Mouse MME/CD10/Neprilysin Protein(His Tag)
货号:GPEM0281
价格: ¥10400.00 ¥3600.00 ¥1200.00 ¥16000.00
产品详情
MME
Alternate NamesAtriopeptidase;CALLA;Enkephalinase;EPN;NEP;Neprilysin;neprilysin-390;neprilysin-411;SFE;Skin fibroblast elastase;Mme;NEP;gp100
Calculated Mw31.8 kDa
Observed Mw32 kDa
Swissprot BackgroundCD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.
StorageGenerally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.