Recombinant Mouse IL-1 beta/IL1B Protein

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Recombinant Mouse IL-1 beta/IL1B Protein-1

货号：GPEM0209

规格：

500 μg 100 μg 20 μg 1 mg

产品详情

Abbre

IL-1 beta

Alternate Names

IL1F;catabolin;Il-1b;IL1-BETA;IL-1beta;IL1F2;Il1b;Interleukin-1 beta;IL-1 beta

Calculated Mw

17.4 kDa

Observed Mw

16 kDa

Swissprot

P10749

Background

Interleukin-1 (IL-1) designates two proteins, IL-1α and IL-1β, which are the products of distinct genes, but recognize the same cell surface receptors. IL-1α and IL-1β are structurally related polypeptides that show approximately 25% homology at the amino acid level. Both proteins are produced by a wide variety of cells in response to stimuli such as those produced by inflammatory agents, infections, or microbial endotoxins. The proteins are synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17.5 kDa. The specific protease responsible for the processing of IL-1β, designated interleukin 1β-converting enzyme (ICE), has been described. Mature human and mouse IL-1β share approximately 75% amino acid sequence identity and human IL-1β has been found to be active on murine cell lines.

Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.