Recombinant Human TGF beta 1 Protein(His Tag)

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Recombinant Human TGF beta 1 Protein(His Tag)-1

货号：GPMH0131

规格：

500 μg 100 μg 20 μg 1 mg

产品详情

Abbre

TGF beta 1

Alternate Names

LAP;Latency-Associated Peptide;TGF-Beta-1;TGFB;TGFB1;Transforming Growth Factor Beta-1

Calculated Mw

42.8 kDa

Observed Mw

48 kDa

Swissprot

P01137

Background

Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.