Recombinant Human ECF/CCL11 Protein(Sumo Tag)

ECF/CCL11

C-C motif chemokine 11;CCL 11;CCL11;CCL11;chemokine (C-C motif) ligand 11;Chemokine C C motif ligand 11;Chemokine CC Motif Ligand 11;Chemokine ligand 11;Eosinophil chemotactic protein;Eotaxin;eotaxin-1;MGC22554;SCYA 11;SCYA11;Small inducible cytokine A11;Small inducible cytokine subfamily A (Cys Cys) member 11;small inducible cytokine subfamily A (Cys-Cys);member 11 (eotaxin);Small inducible cytokine subfamily A member 11;Small-inducible cytokine A11

24.1 kDa

28 kDa

P51671

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.