Recombinant Human CD5L/hAIM Protein(His Tag)

说明书

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Recombinant Human CD5L/hAIM Protein(His Tag)-1

货号：GPMH0080

规格：

500 μg 100 μg 20 μg 1 mg

产品详情

Abbre

CD5L

Alternate Names

API6;Apoptosis inhibitor expressed by macrophages;CD5 antigen-like;CD5L;CT-2;IgM-associated peptide;SP-alpha;UNQ203/PRO229;hAIM

Calculated Mw

38.1 kDa

Observed Mw

42 kDa

Swissprot

O43866

Background

CD5 Antigen-Like (CD5L) is a soluble protein that belongs to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. CD5L is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues. It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram-negative bacteria and the SRCR domain one of CD5L retains both the LPS and LTA binding activities. Furthermore, CD5L seems to play a role as an inhibitor of apoptosis.

Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.