Purified Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]

CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

T-cell membrane protein;T-cell immunoglobulin mucin receptor;T-cell immunoglobulin and mucin domain-containing protein;Tim;TIM-;Tim3;Timd;TIM-3;Timd3;HAVcr-2;Hepatitis A virus cellular receptor 2 homolog;T-cell immunoglobulin and mucin domain-containing protein 3;T-cell immunoglobulin mucin receptor 3;T-cell membrane protein 3;TIMD-3;Havcr2;T cell immunoglobulin and mucin domain containing 3 protein; hepatitis virus cellular receptor 2;TIM-;Tim3;TIM-3;Timd;Timd3

Q8VIM0

Recombinant Mouse CD366/Tim-3 protein

RMT3-23

Rat

Mouse

Rat IgG2a, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag