Purified Anti-Mouse CD172a Antibody[P84]
C57/BL6 Mouse bone marrow were stained with 0.2 μg Purified Anti-Mouse CD172a Antibody[P84] (Right) and 0.2 μg Rat IgG1, κ Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
货号：GF1286A
价格： ￥400.00 ￥1180.00
产品详情
Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization. Receptor for THBS1. Interaction with THBS1 stimulates phosphorylation of SIRPA. In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production.
Alternate NamesMyd;SHPS;Ptpns;Bit;Myd1;Ptpns1;Shps1;Sirp;Sirpa; SIRP&beta-1-1;SIRPαSIRPβAI835480;CD172a;P84;SHP-1;SHPS-1
Swissprot ImmunogenRecombinant Mouse CD172a protein
Clone No. HostRat
ReactivityMouse
IsotypeRat IgG1, κ
DilutionFCM 2 μg/mL(1×105-5×105 cells)
ConjugateUnconjugated
Concentration≥ 1 mg/mL
Purification Method>98%, Protein A/G purified
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date12个月
ShippingIce bag
产品结果图
C57/BL6 Mouse bone marrow were stained with 0.2 μg Purified Anti-Mouse CD172a Antibody[P84] (Right) and 0.2 μg Rat IgG1, κ Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57/BL6 Mouse bone marrow were stained with 0.2 μg Purified Anti-Mouse CD172a Antibody[P84] (Right) and 0.2 μg Rat IgG1, κ Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.