Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7]

CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

Tumor necrosis factor receptor;CD120b;p75;p75TNFR;p80 TNF-alpha receptor;TBPII;TNFBR;TNFR1B;TNF-R2;TNF-R75;TNFR80;TNFR-II;TNF-RII;TNF-R-II;Tumor necrosis factor receptor 2;Tumor necrosis factor receptor superfamily member 1B;Tnfr-2;Tnfr2;Tnfrsf1b; p80; TNFRSF1b;TNFalpha-R2;TNF-alphaR2;Tnfr-1;TNFRII

P25119

Recombinant Mouse CD120b/TNFR2 protein

TR75-54.7

Armenian Hamster

Mouse

Armenian Hamster IgG

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM;Block

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag