Purified Anti-Mouse CD107a Antibody[1D4B]

CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

LGP;lysosomal membrane glycoprotein;Lysosome-associated membrane glycoprotein;120 kDa lysosomal membrane glycoprotein;CD107 antigen-like family member A;CD107a;LGP-120;LGP-A;lysosomal membrane glycoprotein 1;Lysosomal membrane glycoprotein A;Lysosome-associated membrane glycoprotein 1;lysosome-associated membrane protein 1;P2B;Lamp-1;Lamp1; LGP-120

P11438

Recombinant Mouse CD107a protein

1D4B

Rat

Mouse

Rat IgG2a, κ

Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Mouse CD107a gene

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

PBS, pH 7.2. Contains 0.05% proclin 300.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag