Purified Anti-Human CD80 Antibody[2F4]

B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.

LAB;CTLA-4 counter-receptor B;T-lymphocyte activation antigen CD;B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;LAB7;CD80;CD28LGB7-1 antigen;T-lymphocyte activation antigen CD80;Activation B7-1 antigen;CTLA-4 counter-receptor B7.1; B7-1; BB1;B lymphocyte activation antigen B7;B7-1 antigen;B7-1 antigen);CD28 antigen ligand 1;CD80 antigen;CD80 antigen (CD28 antigen ligand 1;CD80 molecule;Costimulatory factor CD80;costimulatory molecule variant IgV-CD80

P33681

Recombinant Human CD80 protein

2F4

Mouse

Human

Mouse IgG1, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag