Purified Anti-Human CD47 Antibody[CC2C6D4]
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD47 Antibody[CC2C6D4] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
货号：GF1060A
价格： ￥700.00 ￥2680.00
产品详情
CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Alternate NamesMER;Protein MER;Leukocyte surface antigen CD;Antigenic surface determinant protein OA;CD47;IAP;MER6;OA3;Integrin-associated protein;Leukocyte surface antigen CD47;Antigenic surface determinant protein OA3;Integrin-associated protein (IAP);Protein MER6;Antigen identified by monoclonal 1D8;CD 47;CD47 antigen;CD47 antigen (Rh-related antigen;CD47 glycoprotein;CD47 molecule;Integrin Associated Protein;Integrin associated signal transducer;integrin-associated signal transducer);MER 6;OA 3;OTTHUMP00000041152;OTTHUMP00000041153;Rh related antigen;Surface antigen identified by monoclonal 1D8
Swissprot ImmunogenRecombinant Human CD47 protein
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG1, κ
DilutionFCM 2 μg/mL(0.5×106-1×106 cells)
ConjugateUnconjugated
Concentration≥ 1 mg/mL
Purification Method>98%, Protein A/G purified
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Expiration Date12个月
ShippingIce bag
产品结果图
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD47 Antibody[CC2C6D4] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 μg Purified Anti-Human CD47 Antibody[CC2C6D4] (Right) and 0.2 μg Mouse IgG1, κ Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.