Purified Anti-Human CD20 Antibody[2H7]

CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

LEU;CVID;B-lymphocyte antigen CD;Leukocyte surface antigen Leu;B-lymphocyte surface antigen B;Membrane-spanning 4-domains subfamily A member;MS4A1;B1;Bp35;CD20;CVID5;LEU-16;MS4A2;S7;B-lymphocyte antigen CD20;B-lymphocyte surface antigen B1;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 1; Bp35; Ly-44;APY;ATOPY;B lymphocyte antigen CD20;B Lymphocyte Cell Surface Antigen B1;B-lymphocyte cell-surface antigen B1;Bp 35;CD 20;CD20 antigen;CD20 receptor;Fc epsilon receptor I beta chain;Fc Fragment of IgE high affinity I receptor for beta polypeptide;FCER1B;High affinity immunoglobulin epsilon receptor subunit beta;IgE Fc receptor subunit beta;IGEL;IGER;IGHER;LEU 16;LEU16;leukocyte surface antigen Leu 16;Ly44;Membrane spanning 4 domains A1;Membrane spanning 4 domains subfamily A member 2;MGC3969

P11836

Recombinant Human CD20 protein

2H7

Mouse

Human

Mouse IgG2b, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Unconjugated

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

12个月

Ice bag