PE/Cyanine7 Anti-Mouse TNFα Antibody[XT3.11]

TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells, and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is a 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorrhagic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.

Tumor necrosis factor-α;Cachectin;Necrosin;Macrophage cytotoxic factor;Differentiation inducing factor;TNFSF-2;TNF-a;TNF-alpha

P06804

XT3.11

Rat

Mouse

Rat IgG1, κ

PE/Cyanine 7

5 μL/Test

ICFCM

Monoclonal

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

冰袋