PE Anti-Human CD22 Antibody[HIB22]

CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

Siglec2;B-cell receptor CD22;B-lymphocyte cell adhesion molecule;BL-CAM;CD22;Cd22;Lyb-8;Sialic acid-binding Ig-like lectin 2;Siglec-2;T-cell surface antigen Leu-14

P20273

HIB22

Mouse

Human

Mouse IgG1, κ

PE

5 μL/Test

FCM

Monoclonal

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

12个月

冰袋