FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1]
货号:GFH1199UC
价格: ¥2016.00 ¥780.00
产品详情
IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Alternate NamesCTLA-8;CTLA8;Cytotoxic T-lymphocyte-associated antigen 8;IL-17;IL-17A;Interleukin-17A
Clone No. HostRat
ReactivityMouse
IsotypeRat IgG1, κ
ConjugateFITC
Concentration0.5 mg/mL
ApplicationsICFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋