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Elab Fluor® Violet 450 Anti-Human HLA-DQ Antibody[1a3]

说明书
  • Elab Fluor® Violet 450 Anti-Human HLA-DQ Antibody[1a3]-1
  • Elab Fluor® Violet 450 Anti-Human HLA-DQ Antibody[1a3]-2
Elab Fluor® Violet 450 Anti-Human HLA-DQ Antibody[1a3]-1

货号:GFH00421Q

价格: ¥2640.00 ¥1020.00 ¥3960.00

规格:
100 Tests 20 Tests 100 Tests × 2
产品详情
Background

HLA-DQ is also known as MHC class II DQ monomorphic antigen. The major histocompatibility complex is composed of two heterodimeric glycoproteins (α and β chains) with apparent molecular weights of 27 and 32 kD. In contrast to other MHC class II molecules, both polypeptide chains of HLA-DQ are polymorphic, with the α chain showing an extremely high degree of polymorphism. HLA-DQ is expressed on B cells in the peripheral blood, and weakly expressed on activated T cells and some monocytes. HLA-DQ is absent on hematopoietic progenitors, resting T cells, erythrocytes, and platelets. HLA-DQ is expressed after HLA-DR and HLA-DP in hematopoietic development. HLA-DQ presents peptide fragments mainly from degraded intravesicular and extracellular proteins to CD4+ T lymphocytes. Specific alleles of HLA-DQ have been linked to the pathogenesis of several autoimmune diseases (including diabetes), both as a susceptibility and resistance factor depending on the particular polymorphism.

Alternate Names

MHC class II DQ monomorphic antigen;MHC II

Swissprot

P01906

Clone No.

1a3

Host

Mouse

Reactivity

Human

Isotype

Mouse IgG2a, κ

Conjugate

Elab Fluor®Violet 450

Concentration

5 μL/Test

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.

Storage

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiration Date

12个月

Shipping

冰袋

产品结果图

Elab Fluor® Violet 450 Anti-Human HLA-DQ Antibody[1a3]-产品结果图-1

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