Elab Fluor® 700 Anti-Human CD172a/b Antibody[SE5A5]
货号:GFH00317M1
价格: ¥3816.00 ¥1680.00 ¥6864.00
产品详情
CD172a, also known as signal-regulatory protein α (SIRPα), src homology 2 domain-containing phosphatase substrate-1 (SHPS1), PTPNS1, BIT, MFR, and P84, is a 75-110 kD transmembrane glycoprotein involved in receptor tyrosine kinase coupled signaling pathway. It belongs to the Ig superfamily and is primarily expressed on monocytes/macrophages, granulocytes, dendritic cells, and neurons. CD172a serves as a substrate of activated receptor tyrosine kinases (RTKs). The interaction of CD172a intracellular domain with SHP-1 and SHP-2 displays negative signaling in the regulation of leukocyte adhesion and transmigration, T cell activation, macrophage fusion, and phagocytosis. CD47 (IAP) is the extracellular ligand for CD172a. SIRPα was recently demonstrated to be a specifc marker for cardiomyocytes derived from human pluripotent stem cells2.
Alternate NamesSIRPa;SIRPb;SIRPalpha/beta;BIT;SHPS1;MFR;P84;PTPNS1;CD172 antigen-like family member A;CD172 antigen-like family member B
Swissprot Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG1, κ
ConjugateElab Fluor®700
ApplicationsFCM
ClonalityMonoclonal
Storage BufferPhosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
StorageThis product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration Date12个月
Shipping冰袋