Biotin Anti-Mouse CD40 Antibody[FGK4.5/FGK45]

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

B-cell surface antigen CD40;Bp50;CD40;CD40L receptor;Cd40;Tnfrsf5;Tumor necrosis factor receptor superfamily member 5

P27512

FGK4.5/FGK45

Rat

Mouse

Rat IgG2a, κ

Biotin

0.5 mg/mL

FCM

Monoclonal

Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.

This product can be stored at 2-8°C for 12 months. Do not freeze.

12个月

冰袋