AF/LE Purified Anti-Mouse CD86 Antibody[GL-1]

文献(5) 说明书

C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Mouse CD86 Antibody[GL-1] (Right) and 0.2 μg Rat IgG2a, κ Isotype Control (Left), followed by PE-conjugated Goat Anti-Rat IgG Secondary Antibody.

货号：GF09940

规格：

100 μg 1 mg

产品详情

Background

CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Alternate Names

CLS;ETC;T-lymphocyte activation antigen CD;Early T-cell costimulatory molecule;TS/A;Cd28l;Activation B7-2 antigen;B7;B7.2;B70;B7-2;Cd28l2;CLS1;Early T-cell costimulatory molecule 1;ETC-1;Ly58;Ly-58;MB7;MB7-2;T-lymphocyte activation antigen CD86;TS/A-2;Cd86; B7-2; Ly-58;sCD86

Swissprot

P42082

Immunogen

Recombinant Mouse CD86 protein

Clone No.

GL-1

Host

Rat

Reactivity

Mouse

Isotype

Rat IgG2a, κ

Dilution

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Conjugate

None (AF/LE)

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiration Date

12个月

Shipping

Ice bag