AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]

C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173] (Right) and 0.2 μg Armenian Hamster IgG, κ Isotype Control (Left), followed by PE-conjugated Goat Anti-Armenian Hamster IgG Secondary Antibody.

货号：GF11140

规格：

100 μg 1 mg

产品详情

Background

CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Alternate Names

CD183/CXCR;C-X-C chemokine receptor type;Cmkar;CXC-R;CD183/CXCR3;C-X-C chemokine receptor type 3;CXCR-3;CXC-R3;Interferon-inducible protein 10 receptor;IP-10 receptor;Cmkar3;Cxcr3;CD_antigen: CD183;CD182;CD183;CKR-L2;C-X-C motif chemokine receptor 3;G protein-coupled receptor 9;GPR9;IP10-R;MigR;Mig-R

Swissprot

O88410

Immunogen

Recombinant Mouse CD183/CXCR3 protein

Clone No.

CXCR3-173

Host

Armenian Hamster

Reactivity

Mouse

Isotype

Armenian Hamster IgG

Dilution

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Conjugate

None (AF/LE)

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM;Block

Clonality

Monoclonal

Storage Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiration Date

12个月

Shipping

Ice bag