AF/LE Purified Anti-Mouse CD18 Antibody[M18/2]

C57/BL6 Mouse splenocytes were stained with 0.2 μg AF/LE Purified Anti-Mouse CD18 Antibody[M18/2] (Right) and 0.2 μg Rat IgG2a, κ Isotype Control (Left), followed by Elab Fluor^® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.

货号：GF11130

规格：

100 μg 1 mg

产品详情

Background

CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

Alternate Names

Integrin beta;ITGB;CD18;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;Integrin beta-2;Itgb2;&beta-2 integrin-n

Swissprot

P11835

Immunogen

Recombinant Mouse CD18 protein

Clone No.

M18/2

Host

Rat

Reactivity

Mouse

Isotype

Rat IgG2a, κ

Verified Samples

Verified Samples in FCM: C57/BL6 Mouse splenocytes

Dilution

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

Conjugate

None (AF/LE)

Concentration

≥ 1 mg/mL

Purification Method

>98%, Protein A/G purified

Applications

FCM

Clonality

Monoclonal

Storage Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Storage

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Expiration Date

12个月

Shipping

Ice bag