AF/LE Purified Anti-Mouse CD132 Antibody[3E12]

CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

CD132;Cytokine receptor common subunit gamma;gammaC;IL-2 receptor subunit gamma;IL-2R subunit gamma;IL-2RG;Interleukin-2 receptor subunit gamma;p64;Il2rg;common &gamma- chain-n; IL-2Rγgamma(c)

P34902

Recombinant Mouse CD132 protein

3E12

Rat

Mouse

Rat IgG2b, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

None (AF/LE)

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag