AF/LE Purified Anti-Mouse CD119 Antibody[GR-20]

CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

CDw;IFN-gamma-R;IFN gamma receptor;IFN-gamma receptor;immune interferon receptor;INGR;IFN-γ R;CD119;CD119 antigen;CDw119;Ifgr;IFN gamma receptor 1;IFN-gamma receptor 1;IFN-gammaR;IFN-gamma-R1;IFN-gamma-R-alpha;IFN-γ R1;immune interferon receptor 1;INGR1;Interferon gamma receptor 1;Interferon gamma receptor alpha-chain;interferon-gamma receptor alpha chain;Nktar;Ifngr;Ifngr1;IFN&gamma-R-R; IFN&gamma-Ra-a; CDw119;Interferon gamma receptor 1;IFNGR1;INGR1;IFN-gamma receptor 1;IFN-gamma-R1;CDw119;Interferon gamma receptor alpha-chain;IFN-gamma-R-alpha;CD119

P15261

Recombinant Mouse CD119 protein

GR-20

Rat

Mouse

Rat IgG2a, κ

FCM 2 μg/mL(1×10⁵-5×10⁵ cells)

None (AF/LE)

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag