AF/LE Purified Anti-Human IL-9 Antibody[MH9A4]

IL-9 is a 14 kDa cytokine originally named P40 and identified by its proliferative effects on T cell populations. The receptor, which is a heterodimer of the gamma chain portion of the IL-2 receptor and the IL-9R chain, activates Jak/STAT signaling pathways upon binding its ligand. Since the discovery of IL-9, numerous other functions have been observed. It induces Th17 and Treg differentiation in CD4+ T cells, IgE production in B cells, and the differentiation and proliferation of mast cells. IL-9 expression was initially observed in Th2 cells, but has since been found in Th17, eosinophil, and mast cells. Th9 cells, a newly discovered subset of CD4+ T cells, are characterized by the secretion of large amounts of IL-9 and IL-10. Th9 development is induced by stimulation of undifferentiated CD4+ with IL-4 and TGF beta. Th2 cells can also be driven towards a Th9 phenotype in the presence of TGF beta.

Cytokine P;Interleukin;TCGF;IL9;HP40;IL-9;P40;Cytokine P40;Interleukin-9;P40 Cytokine;P40 T-cell and Mast Cell Growth Factor;T-cell Growth Factor P40;TCGF3;TCGFIII

P15248

Recombinant Human IL-9 protein

MH9A4

Mouse

Human

Mouse IgG2b,κ

Verified Samples in FCM: HEK293T cells transfected with pcDNA3.1 plasmid encoding Human IL-9 gene

FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

None (AF/LE)

≥ 1 mg/mL

>98%, Protein A/G purified

FCM

Monoclonal

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

12个月

Ice bag