AF/LE Purified Anti-Human CD8a Antibody[OKT-8]
Human peripheral blood lymphocytes were stained with 0.2 μg AF/LE Purified Anti-Human CD8a Antibody[OKT-8] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
货号：GF11100
价格： ￥420.00 ￥1248.00
产品详情
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Alternate NamesLeu;T-lymphocyte differentiation antigen T8/Leu;CD8A;CD8;Leu2;MAL;p32;T8;T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2; CD8; Leu-2; Ly-2;alpha polypeptide (p32);CD8 antigen alpha polypeptide;CD8 antigen alpha polypeptide (p32);CD8A antigen;CD8A molecule;Leu2 T lymphocyte antigen;Ly3;LYT3;OKT8 T cell antigen;OTTHUMP00000160760;OTTHUMP00000160764;OTTHUMP00000203528;OTTHUMP00000203721;T cell antigen Leu2;T cell co receptor;T8 T cell antigen;T8/Leu-2 T-lymphocyte differentiation antigen
Swissprot ImmunogenRecombinant Human CD8a protein
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG2a, κ
DilutionFCM 2 μg/mL(1×105-5×105 cells)
ConjugateNone (AF/LE)
Concentration≥ 1 mg/mL
Purification Method>98%, Protein A/G purified
ApplicationsFCM;Depletion
ClonalityMonoclonal
Storage BufferSterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Expiration Date12个月
ShippingIce bag
产品结果图
Human peripheral blood lymphocytes were stained with 0.2 μg AF/LE Purified Anti-Human CD8a Antibody[OKT-8] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 μg AF/LE Purified Anti-Human CD8a Antibody[OKT-8] (Right) and 0.2 μg Mouse IgG2a, κ Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.