产品详情
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
Alternate NamesEBI;CDw;BLR;EVI;CMKBR;CC-CKR;CCR;CCR7;BLR2;CC-CKR-7;CCR-7;CD197;CDw197;CMKBR7;EBI1;EVI1; EBI-1; BLR-2; CMKBR7
Swissprot ImmunogenRecombinant Human CD197 protein
Clone No. HostMouse
ReactivityHuman
IsotypeMouse IgG2a, κ
DilutionFCM 2 μg/mL(1×105-5×105 cells)
ConjugateNone (AF/LE)
Concentration≥ 1 mg/mL
Purification Method>98%, Protein A/G purified
ApplicationsFCM
ClonalityMonoclonal
Storage BufferSterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Expiration Date12个月
ShippingIce bag